Protein Modification Screening Tool
(ProMoST)

Program to calculate accurate MWT and pI values from proteins


Accession Numbers:


File of Accession numbers to upload:


pK values

Basic Amino Acids

AAPrimaryN-TerminalC-Terminal
K
R
H

Acidic Amino Acids

AAPrimaryN-TerminalC-Terminal
D
E
C
Y

Terminal Amino Acids

Amino AcidN-termC-Term
G
A
S
P
V
T
C
I
L
N
D
Q
K
E
M
H
F
R
Y
W

Protein Modifications

Terminal Ends Blocked
N Terminus C Terminus Both ends

Deamidation
Asparagine(N) Glutamine(Q)

Phosphorylation
Phosphoserine/threonine(S/T) pKa1 pKa2
Phosphotyrosine(Y) pKa1 pKa2

Additional Modifications
Modification 1 Name Charge pKa1 pKa2
Modification 2 Name Charge pKa1 pKa2
Modification 3 Name Charge pKa1 pKa2

Display options:

Input Sequence Title Lines Amino Acid Sequence Amino Acid Composition

Output locations:

Display on Screen Save to Tab Delim Text File
Plot gel image
Low pH High pH pH step
Low MWT (kDa) High MWT (kDa) MWT step (kDa)

Output options:

Detailed header Column headings Input Acc. Numbers Acc. Numbers Sequence description
Monoisotopic mass Average isotopic mass pI